Concepts And Case Studies In Chemical Biology PDF Download

Concepts and Case Studies in Chemical Biology PDF
Author: Herbert Waldmann
Publisher: John Wiley & Sons
Size: 31.77 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 464
View: 6511

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Retaining the proven didactic concept of the successful "Chemical Biology - Learning through Case Studies", this sequel features 27 new case studies, reflecting the rapid growth in this interdisciplinary topic over the past few years. Edited by two of the world's leading researchers in the field, this textbook introduces students and researchers to the modern approaches in chemical biology, as well as important results, and the techniques and methods applied. Each chapter presents a different biological problem taken from everyday lab work, elucidated by an international team of renowned scientists. With its broad coverage, this is a valuable source of information for students, graduate students, and researchers working on the borderline between chemistry, biology, and biochemistry.

Chemical Biology Of Glycoproteins PDF Download

Chemical Biology of Glycoproteins PDF
Author: Zhongping Tan
Publisher: Royal Society of Chemistry
Size: 64.61 MB
Format: PDF, Docs
Category : Glycoproteins
Languages : en
Pages : 421
View: 6985

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Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions. Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.

Chemical Biology PDF Download

Chemical Biology PDF
Author: Herbert Waldmann
Publisher: Wiley-VCH
Size: 32.52 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 207
View: 7315

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The present selection of 12 inspiring experiments has been carefully selected to cover the most commonly used laboratory techniques for the synthesis and analysis of bioactive compounds. Together, they provide a solid introduction to the skills and techniques that are required for the successful study of Chemical Biology.. Here you will learn how to * synthesize a peptide by solid phase synthesis * modify a protein by covalent attachment of a lipid chain * modify an oligonucleotide and use it for DNA-directed immobilization * isolate an enzyme for in vitro synthesis of a polysaccharide * design a ligand for a protein by molecular modeling * perform a proteome analysis in yeast All experiments haven been thoroughly tested in the authors' laboratory and come with an easy to follow step-by-step instruction, complemented by abundant practical hints and by a thorough treatment of the underlying theory and mechanisms.

Innovations In Chemical Biology PDF Download

Innovations in Chemical Biology PDF
Author: Bilge Sener
Publisher: Springer Science & Business Media
Size: 61.10 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 428
View: 421

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This book includes 49 chapters presented as plenary , invited lectures and posters at the conference. Six plenary lectures have published in an issue of Pure and Applied Chemistry, Vol. 79, No. 12, 2007; the titles of these presentations are given as an Annex at the end of the book. I thank all contrib utors for the preparation of their presentations. It is sad to report that Professor Hitoshi Ohtaki, one of the founders of the Eurasia conferences and contributors passed away on November 5, 2006. Professor Ohtaki enthusiastically promoted international cooperation and took it upon himself to p- licize Japanese science to the wider world. His contribution in this book will serve as a memorable contribution to that goal. He will be missed by all of us. This book is dedicated to his memory. Professor Dr . Bilge S ̧ ener Editor Memorial Tribute to Professor Dr. Hitoshi Ohtaki Curriculum Vitae of Hitoshi Ohtaki Date of Birth September 16, 1932 Place of Birth T ok yo, Japan Date of Decease November 5, 2006 (at the age of 74) Addr ess 3-9-406 Namiki-2-chome, Kanazawa-ku, Yokohama, Japan Institution Chair Professor of The Research Organization of Science and Engineering, Ritsumeikan University Guest Professor of Yokohama City University Education Bachelor of Science, Nagoya University, 1955 Master of Science, Nagoya University, 1957 Doctor of Science, Nagoya University, 1961 ix x Memorial Tribute to Professor Dr.

Chemical Biology Selected Papers Of H G Khorana With Introductions PDF Download

Chemical Biology  Selected Papers Of H G Khorana  With Introductions  PDF
Author: H Gobind Khorana
Publisher: World Scientific
Size: 38.19 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 632
View: 1786

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The first two chapters of this invaluable book trace the developments of the chemistry and macromolecular structures, respectively, of proteins and nuclei acids. Similarly, the introductions to the succeeding chapters review, step by step, the historical landmarks in the topics covered. These include discoveries of biological phosphate esters, nucleotides and nucleotide coenzymes (important in intermediary metabolism), the nature of the genetic material and biological synthesis of proteins, formulation of the problem of the genetic code, and perspectives on bioenergetics.The selected papers illustrate the developments of the chemical synthesis of nucleotides and nucleotide coenzymes of ribo- and deoxy-ribo-polynucleotides (RNA, DNA), of the total synthesis of genes in the laboratory, and principles for gene amplification (PCR). Another major section covers studies of enzymes that degrade nucleic acids, the structure of transfer RNA and its role in protein synthesis, and the author's work on the elucidation of the genetic code. Finally, there are descriptions of the studies on biological membranes and the membrane protein bacteriorhodopsin, a biological proton pump. These studies elucidated the mechanism of proton translocation, which is central to bioenergetics.

Chemical Biology PDF Download

Chemical Biology PDF
Author: Deniz Ekinci
Publisher: IntechOpen
Size: 63.96 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 446
View: 6908

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Chemical biology utilizes chemical principles to modulate systems to either investigate the underlying biology or create new function. Over recent years, chemical biology has received particular attention of many scientists in the life sciences from botany to medicine. This book contains an overview focusing on the research area of protein purification, enzymology, vitamins, antioxidants, biotransformation, gene delivery, signaling, regulation and organization. Particular emphasis is devoted to both theoretical and experimental aspects. The textbook is written by international scientists with expertise in synthetic chemistry, protein biochemistry, enzymology, molecular biology, drug discovery and genetics many of which are active chemical, biochemical and biomedical research. The textbook is expected to enhance the knowledge of scientists in the complexities of chemical and biological approaches and stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of chemical biology.

Chemical Biology PDF Download

Chemical Biology PDF
Author: Natanya Civjan
Publisher: John Wiley & Sons
Size: 52.32 MB
Format: PDF
Category : Science
Languages : en
Pages : 524
View: 2758

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An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.

Chemical Biology Of Sterols Triterpenoids And Other Natural Products PDF Download

Chemical Biology of Sterols  Triterpenoids and Other Natural Products PDF
Author: Wenxu Zhou
Publisher: MDPI
Size: 62.82 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 256
View: 423

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Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.

Introduction To Bioorganic Chemistry And Chemical Biology PDF Download

Introduction to Bioorganic Chemistry and Chemical Biology PDF
Author: David Van Vranken
Publisher: Garland Science
Size: 70.45 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 504
View: 6598

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Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations and mechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology. Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science.

Chemistry And Chemical Biology PDF Download

Chemistry and Chemical Biology PDF
Author: Roman Joswik
Publisher: CRC Press
Size: 20.31 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 312
View: 2556

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This important volume highlights the latest developments and trends in chemistry, biochemistry, and biology. It presents the developments of advanced materials and respective tools to characterize and predict the material properties and behavior. The book provides original, theoretical, and important experimental results that use non-routine methodologies often unfamiliar to the usual readers. The papers on novel applications of more familiar experimental techniques and analyses of chemical, biochemistry, and biological programs indicate the need for new experimental approaches.