Pharmaceutical Biotechnology PDF Download

Pharmaceutical Biotechnology PDF
Author: Gary Walsh
Publisher: John Wiley & Sons
Size: 44.62 MB
Format: PDF
Category : Science
Languages : en
Pages : 504
View: 1255

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Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed

Pharmaceutical Biotechnology PDF Download

Pharmaceutical Biotechnology PDF
Author: Daan J. A. Crommelin
Publisher: Springer Science & Business Media
Size: 30.35 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 544
View: 6007

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This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pharmaceutical industry. The Fourth Edition will completely update the previous edition, and will also include additional coverage on the newer approaches such as oligonucleotides, siRNA, gene therapy and nanotech.

Pharmaceutical Biotechnology PDF Download

Pharmaceutical Biotechnology PDF
Author: Carlos A. Guzmán
Publisher: Springer Science & Business Media
Size: 61.87 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 276
View: 2687

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Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins and vaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens’ genomes provides opportunities that never before have been available—identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated, replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process. The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.

Pharmaceutical Biotechnology PDF Download

Pharmaceutical Biotechnology PDF
Author: Oliver Kayser
Publisher: John Wiley & Sons
Size: 58.98 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 676
View: 1733

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This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.

Handbook Of Pharmaceutical Biotechnology PDF Download

Handbook of Pharmaceutical Biotechnology PDF
Author: Shayne Cox Gad
Publisher: John Wiley & Sons
Size: 24.44 MB
Format: PDF, Docs
Category : Medical
Languages : en
Pages : 1680
View: 7442

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A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in their specialty areas, this reference: Provides an overview of biotechnology used in the drug development process Covers extensive applications, plus regulations and validation methods Features fifty chapters covering all the major approaches to the challenge of identifying, producing, and formulating new biologically derived therapeutics With its unparalleled breadth of topics and approaches, this handbook is a core reference for pharmaceutical scientists, including development researchers, toxicologists, biochemists, molecular biologists, cell biologists, immunologists, and formulation chemists. It is also a great resource for quality assurance/assessment/control managers, biotechnology technicians, and others in the biotech industry.

Excipient Development For Pharmaceutical Biotechnology And Drug Delivery Systems PDF Download

Excipient Development for Pharmaceutical  Biotechnology  and Drug Delivery Systems PDF
Author: Ashok Katdare
Publisher: CRC Press
Size: 52.21 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 452
View: 5784

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To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new excipients to be developed and approved continues to increase. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems serves as a comprehensive source to improve understanding of excipients and forge new avenues for regulatory review and allowance to use. This book presents detailed, up-to-date information on various aspects of excipient development, testing, and technological considerations for their use. It addresses specific details such as historical perspective, preclinical testing, safety, and toxicology evaluation, as well as regulatory, quality, and utility aspects. The text also describes best practices for use of various functional excipients and extensive literature references for all topics.

Innovation In Pharmaceutical Biotechnology Comparing National Innovation Systems At The Sectoral Level PDF Download

Innovation in Pharmaceutical Biotechnology Comparing National Innovation Systems at the Sectoral Level PDF
Author: OECD
Publisher: OECD Publishing
Size: 28.17 MB
Format: PDF, Kindle
Category :
Languages : en
Pages : 187
View: 5810

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This publication examines the innovation system in pharmaceutical biotechnology in eight OECD countries - Belgium, Finland, France, Germany, Japan, the Netherlands, Norway and Spain - and makes recommendations advocating an integrated policy approach.

Pharmaceutical Biotechnology And Chemical Inventions PDF Download

Pharmaceutical  Biotechnology  and Chemical Inventions PDF
Author: Duncan Bucknell
Publisher: Oxford University Press, USA
Size: 78.57 MB
Format: PDF, ePub
Category : Law
Languages : en
Pages : 2100
View: 6148

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Pharmaceutical, Biotechnology, and Chemical Inventions: World Protection and Exploitation, This book highlights the special issues arising in obtaining, commercializing, enforcing or attacking intellectual property rights (including protection of regulatory data) in the pharmaceutical, biotechnology and chemical industries across the world's key jurisdictions. It is unique in presenting topic matter horizontally by subject to facilitate comparison between country practices. The first two chapters give a general introduction to the differences between the jurisdictions and an overview of some of the key concepts in patent law. The remainder of the book is dedicated to a detailed analysis of the major legal issues arising in these areas of technology. Each component chapter has a comparative introduction, looking at the variances in the laws of different domains, followed by side-by-side analysis of the relevant regimes, including tables and flow-charts which summarize and explain the key legal concepts. The jurisdictions covered are the United States, Europe (UK, Germany, Netherlands, France and Italy), Japan, Canada, Australia, India and China.

Pharmaceutical Biotechnology Fundamentals And Application PDF Download

Pharmaceutical Biotechnology Fundamentals and Application PDF
Author: Chandrakant Kokare
Publisher: Nirali Prakashan
Size: 76.65 MB
Format: PDF, Mobi
Category : Study Aids
Languages : en
Pages : 358
View: 5985

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Introduction and Scope of Biotechnology - Development of Industrial Strains - Fermentation Process - Production of Pharmaceuticals - Microbial Biotransformation - Introduction to Genetics - DNA Replication, Transcription and Translation - Genetic Recombination Gene Transfer - Recombinant DNA Technology Gene Cloning - Techniques of Genetic Engineering - Healthcare Biotechnology - Enzyme Technology - Plant Cell Culture - Animal Cell Culture - Appendices - I -II- Index